Rodent Model as Tools in Ethical Biomedical Research PDF Download

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Rodent Model as Tools in Ethical Biomedical Research

Rodent Model as Tools in Ethical Biomedical Research PDF Author: Monica Levy Andersen
Publisher: Springer
ISBN: 9783319791715
Category : Medical
Languages : en
Pages : 516
Book Description
​The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.

Rodent Model as Tools in Ethical Biomedical Research

Rodent Model as Tools in Ethical Biomedical Research PDF Author: Monica Levy Andersen
Publisher: Springer
ISBN: 9783319791715
Category : Medical
Languages : en
Pages : 516
Book Description
​The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.

Rodent Model as Tools in Ethical Biomedical Research

Rodent Model as Tools in Ethical Biomedical Research PDF Author: Monica Levy Andersen
Publisher: Springer
ISBN: 3319115782
Category : Medical
Languages : en
Pages : 516
Book Description
​The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.

Sleep Medicine and Physical Therapy

Sleep Medicine and Physical Therapy PDF Author: Cristina Frange
Publisher: Springer Nature
ISBN: 3030850749
Category : Medical
Languages : en
Pages : 431
Book Description
Sleep is considered one of the vital signs and has become an important public health issue in our society. Thus, sleep impacts on overall health and, conversely, certain common medical conditions can impair sleep. Emerging evidence, in conjunction with clinical experience, demonstrates that physical therapy improves several sleep disorders and also optimized sleep contributes to boost rehabilitation. As health care professionals, physical therapists are singularly concerned with well-being and need to be competent to instruct their patients to rest and sleep. This book discusses evidences of physiotherapy and sleep medicine. It elucidates the neurophysiological background and mechanisms for physiotherapeutic resources and techniques, directing the future for promising research in the area. Divided in seven sections, the work initially addresses the basic concepts of sleep and physiotherapy and its relation to practice, including the importance of sleep medicine for health. The second section focuses on the basic conceptions of physical therapists' understanding and working in clinical practice and research with sleep.The next section reviews the most common sleep disturbances such as insomnia, restless legs syndrome, and respiratory sleep disturbances. Special populations, spotlighting childhood and adolescence, women physiologic reproductive stages, sleep and gender, and sleep and pain interactions are also examined. Last sections discuss the physical therapy resources to improve sleep and to treat sleep disturbances. This title is an essential resource not only for graduate students, residents, health professionals and physiotherapists working in prevention and rehabilitation, but also for researchers interested in screening, diagnostic and treatment innovations. It is addressed to neurologists, sleep medicine specialists and physical educators as well.

Phytochemistry, 3-Volume Set

Phytochemistry, 3-Volume Set PDF Author: Chukwuebuka Egbuna
Publisher: CRC Press
ISBN: 0429760485
Category : Health & Fitness
Languages : en
Pages : 1806
Book Description
The 3-volume set, Phytochemistry, covers a wide selection of topics in phytochemistry and provides a wealth of information on the fundamentals, new applications, methods and modern analytical techniques, state-of-the-art approaches, and computational techniques. With chapters from professional specialists in their fields from around the world, the volumes deliver a comprehensive coverage of phytochemistry. Phytochemistry is a multidisciplinary field, so this book will appeal to students in both upper-level students, faculty, researchers, and industry professionals in a number of fields, including biological science, biochemistry, pharmacy, food and medicinal chemistry, systematic botany and taxonomy, ethnobotany, conservation biology, plant genetic and metabolomics, evolutionary sciences, and plant pathology.

Phytochemistry

Phytochemistry PDF Author: Chukwuebuka Egbuna
Publisher: CRC Press
ISBN: 0429760329
Category : Health & Fitness
Languages : en
Pages : 665
Book Description
This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.

The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish PDF Author: Allan V. Kalueff
Publisher: Springer
ISBN: 3319337742
Category : Medical
Languages : en
Pages : 327
Book Description
Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book “The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling” explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.

Behavioral Biology of Laboratory Animals

Behavioral Biology of Laboratory Animals PDF Author: Kristine Coleman
Publisher: CRC Press
ISBN: 0429671296
Category : Medical
Languages : en
Pages : 560
Book Description
This 30-chapter volume informs students and professionals about the behavioral biology of animals commonly housed in laboratory and other captive settings. Each species evolved under specific environmental conditions, resulting in unique behavioral patterns, many of which are maintained in captivity even after generations of breeding. Understanding natural behavior is therefore a critical part of modern animal care practices. The descriptions, data, guidance, resources, and recommendations in this book will help the reader understand their animals better, refine the care and treatment that they receive, and improve the well-being, welfare, and wellness of their animals. The book is divided into three sections, all focusing on aspects of the behavioral biology of animals found in laboratories and related research settings. After five introductory chapters, 25 chapters are dedicated to specific taxonomic groups (including mice, zebrafish, zebra finches, reptiles, macaques) while a concluding section of ethograms provides a centralized resource for those interested in understanding, and potentially quantifying, animal behavior. The Behaviorial Biology of Laboratory Animals will provide anyone working in maintenance, care, and/or research programs that involve laboratory animals with information about the way the animals live in the wild, and the way that they should live in captive research settings. Many of the guidelines and recommendations will also be valuable to those managing and working with animals in other environments, including zoological parks, aquaria, and sanctuaries.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070702
Category :
Languages : en
Pages : 10
Book Description
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...

Varicocele and Male Infertility

Varicocele and Male Infertility PDF Author: Sandro C Esteves
Publisher: Springer Nature
ISBN: 3319791028
Category : Health & Fitness
Languages : en
Pages : 638
Book Description
This unique textbook – the first of its kind – presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility. This hot topic is covered from a multitude of angles in seven thematic sections: origin and pathophysiology, clinical evaluation, medical and surgical therapy, controversies, pro and con debates, and clinical case scenarios. The scope of varicocele includes basic and transitional research, genetics, diagnostic testing with conventional and advanced molecular biology approaches, hormonal control, interventional therapy and assisted reproductive technology (ART). Repair of varicocele, which can be carried out by various methods, not only alleviates oxidative stress‐associated infertility but also prevents and protects against the progressive character of varicocele and its consequent upregulations of systemic oxidative stress. Even with the advances in the understanding of this intriguing disease and consensus on some areas such as diagnosis and pathophysiology, substantial controversy still exists, in particular concerning the benefits of treatment and to whom treatment should be offered. Additional chapters discuss, in depth, such controversies surrounding the role of varicocele in male infertility and present clinical case scenarios dealing with management of subclinical and clinical varicocele. A series of editorial comments is provided by the editors at the end of selected chapters, containing an objective and concise summary of the information from each chapter. In addition, chapters open up with key points for quick references and conclude with multiple choice questions and answers for immediate review and retention of the rich content. Generously illustrated, Varicocele and Male Infertility: A Complete Guide represents an invaluable tool for medical students in reproductive medicine as well as researchers and clinicians working in the field of infertility (e.g., urologists, gynecologists, reproductive endocrinologists, and embryologists) and is comprised of chapters written by leading and internationally recognized clinicians and scientists with expertise in varicocele, skillfully edited by leaders in the field.

Cocoa, Chocolate and Human Health

Cocoa, Chocolate and Human Health PDF Author: Sabine Ellinger
Publisher: MDPI
ISBN: 3039285882
Category : Science
Languages : en
Pages : 288
Book Description
This book entitled “Cocoa, Chocolate, and Human Health” presents the most recent findings about cocoa and health in 14 peer-reviewed chapters including nine original contributions and five reviews from cocoa experts around the world. Bioavailability and metabolism of the main cocoa polyphenols, i.e., the flavanols like epicatechin, are presented including metabolites like valerolactones that are formed by the gut microbiome. Many studies, including intervention studies or epidemiological observations, do not focus on single compounds, but on cocoa as a whole. This proves the effectiveness of cocoa as a functional food. A positive influence of cocoa on hearing problems, exercise performance, and metabolic syndrome is discussed with mixed results; the results about exercise performance are contradictive. Evidence shows that cocoa flavanols may modulate some risk factors related to metabolic syndrome such as hypertension and disorders in glucose and lipid metabolism. However, several cardiometabolic parameters in type 2 diabetics were not affected by a flavanol-rich cocoa powder as simultaneous treatment with pharmaceuticals might have negated the effect of cocoa. The putative health-promoting components of cocoa are altered during processing like fermentation, drying, and roasting of cocoa beans. Chocolate, the most popular cocoa product, shows remarkable losses in polyphenols and vitamin E during 18 months of storage.